HSD17B13-IN-82
Product Specifications
CAS Number
2770247-47-5
Target
Dehydrogenase
Related Pathways
Metabolism
Bioactivity
HSD17B13-IN-82 (Compound 156) serves as a potent inhibitor targeting hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), exhibiting an IC 50 of ≤ 0.1 μM against estradiol. This compound is useful in studying various liver and metabolic disorders, including NAFLD, NASH, and drug-induced liver injury (DILI), as well as cardiovascular diseases [1].
Smiles
N(C(=O)C1=CC(Cl)=C(O)C(Cl)=C1)C2=C3C(N=C(C)N(CC4=C(C(F)(F)F)C=CC=C4)C3=O)=C(Cl)C=C2
Molecular Formula
C24H15Cl3F3N3O3
Molecular Weight
556.75
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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