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HSD17B13-IN-80

Product Specifications

CAS Number

2770247-42-0

Target

Dehydrogenase

Related Pathways

Metabolism

Bioactivity

HSD17B13-IN-80 (Compound 151) serves as an inhibitor for hydroxysteroid 17?-dehydrogenase 13 (HSD17B13), demonstrating potent activity with an IC 50 ? 0.1 ?M against estradiol. It is primarily utilized in the investigation of liver, metabolic, and cardiovascular diseases including NAFLD, NASH, and drug-induced liver injury (DILI) [1].

Smiles

N(C(=O)C1=CC(Cl)=C(O)C(Cl)=C1)C2=C3C(N=C(C)N(CC4=C(C(F)(F)F)C=CC=C4)C3=O)=C(C)C=C2

Molecular Formula

C25H18Cl2F3N3O3

Molecular Weight

536.33

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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