HSD17B13-IN-79
Product Specifications
CAS Number
2770246-31-4
Target
Dehydrogenase
Related Pathways
Metabolism
Bioactivity
HSD17B13-IN-79 (Compound 32), an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), demonstrates potent activity with an IC50 value of ≤ 0.1 μM against estradiol. This compound is primarily utilized in the study of liver, metabolic, and cardiovascular diseases, including non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH), and drug-induced liver injury (DILI) [1].
Smiles
N(C(=O)C1=CC(Cl)=C(O)C(Cl)=C1)C2=C(C(NCC3=C(OC(F)(F)F)C=CC=C3)=O)N=CS2
Molecular Formula
C19H12Cl2F3N3O4S
Molecular Weight
506.28
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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