HSD17B13-IN-75
Product Specifications
CAS Number
2770246-20-1
Target
Dehydrogenase
Related Pathways
Metabolism
Bioactivity
HSD17B13-IN-75 (Compound 21) serves as an inhibitor targeting hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), demonstrating an IC 50 value of ≤ 0.1 μM for estradiol. Its applications are primarily in the research fields addressing liver diseases, metabolic disorders, and cardiovascular conditions, including NAFLD, NASH, and drug-induced liver injury (DILI) [1].
Smiles
O=C1N(C2(CC2)C3=C(F)C=CC=C3)C=NC=4C1=C(NC(=O)C5=CC(Cl)=C(O)C(Cl)=C5)C=CC4
Molecular Formula
C24H16Cl2FN3O3
Molecular Weight
484.31
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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