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HSD17B13-IN-71

Product Specifications

CAS Number

2770247-40-8

Target

Dehydrogenase

Related Pathways

Metabolism

Bioactivity

HSD17B13-IN-71 (Compound 149), an effective inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), displays potent activity with an IC 50 value of ≤ 0.1 μM against estradiol. This compound is applicable in the study of various disorders including liver diseases, metabolic diseases, and cardiovascular conditions such as NAFLD or NASH, in addition to drug-induced liver injury (DILI) [1].

Smiles

N(C(=O)C1=CC(Cl)=C(O)C(Cl)=C1)C2=C3C(N=C(C(F)F)N(CC4=C(OC(F)(F)F)C=CC=C4)C3=O)=C(C)C=C2

Molecular Formula

C25H16Cl2F5N3O4

Molecular Weight

588.31

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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