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HSD17B13-IN-7

Product Specifications

CAS Number

863564-16-3

Target

Dehydrogenase, iGluR

Related Pathways

Metabolism, Membrane transporter/Ion channel, Neuroscience

Bioactivity

HSD17B13-IN-7 (compound 1) is a fluorophenol-containing compound that acts as a potent HSD17B13 inhibitor, with IC50 values of 0.18 μM and 0.25 μM using β-estradiol and Leukotriene B4 as substrates, respectively. Additionally, HSD17B13-IN-7 serves as a potent antagonist of the N-methyl-D-aspartate (NMDA) NR2B receptor and shows potential for research on non-alcoholic fatty liver disease [1].

Smiles

C(OC1=CC=CC=C1)[C@H]2CC[C@](CNC(=O)C3=CC(F)=C(O)C=C3)(O)CC2

Molecular Formula

C21H24FNO4

Molecular Weight

373.42

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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