HSD17B13-IN-7
Product Specifications
CAS Number
863564-16-3
Target
Dehydrogenase|||iGluR
Related Pathways
Metabolism|||Membrane transporter/Ion channel|||Neuroscience
Bioactivity
HSD17B13-IN-7 (compound 1) is a fluorophenol-containing compound that acts as a potent HSD17B13 inhibitor, with IC?? values of 0.18 ?M and 0.25 ?M using ?-estradiol and Leukotriene B4 as substrates, respectively. Additionally, HSD17B13-IN-7 serves as a potent antagonist of the N-methyl-D-aspartate (NMDA) NR2B receptor and shows potential for research on non-alcoholic fatty liver disease [1].
Smiles
C(OC1=CC=CC=C1)[C@H]2CC[C@](CNC(=O)C3=CC(F)=C(O)C=C3)(O)CC2
Molecular Formula
C21H24FNO4
Molecular Weight
373.42
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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