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HSD17B13-IN-69

Product Specifications

CAS Number

2770246-16-5

Target

Dehydrogenase

Related Pathways

Metabolism

Bioactivity

HSD17B13-IN-69 (Compound 11) functions as an inhibitor targeting hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), demonstrating potent activity with an IC 50 value of ≤ 0.1 μM against estradiol. This compound has practical applications in studying a variety of conditions including liver, metabolic, and cardiovascular diseases, specifically NAFLD, NASH, and drug-induced liver injury (DILI) [1].

Smiles

N(C(=O)C1=CC(Cl)=C(O)C(Cl)=C1)C2=C3C(N=CN(CC=4C=CN=CC4)C3=O)=CC=C2

Molecular Formula

C21H14Cl2N4O3

Molecular Weight

441.27

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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