HSD17B13-IN-61
Product Specifications
CAS Number
2770247-26-0
Target
Dehydrogenase
Related Pathways
Metabolism
Bioactivity
HSD17B13-IN-61 (Compound 132) acts as an inhibitor against hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), featuring an IC50 value of ≤ 0.1 μM for estradiol. This compound is utilized in the study of various health conditions, including liver diseases, metabolic diseases, and cardiovascular diseases like NAFLD or NASH. It is also relevant in the investigation of drug-induced liver injury (DILI) [1].
Smiles
N(C(=O)C1=CC(Cl)=C(O)C(Cl)=C1)C2=C3C(N=CN(CC4=C(OC(F)(F)F)C=CC=C4)C3=O)=C(F)C=C2
Molecular Formula
C23H13Cl2F4N3O4
Molecular Weight
542.27
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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