HSD17B13-IN-49
Product Specifications
CAS Number
2770246-74-5
Target
Dehydrogenase
Related Pathways
Metabolism
Bioactivity
HSD17B13-IN-49 (Compound 81) acts as an inhibitor targeting hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), demonstrating an IC50 value of ≤ 0.1 μM for estradiol. It is utilized in studies exploring liver, metabolic, and cardiovascular diseases, including NAFLD, NASH, and drug-induced liver injury (DILI) [1].
Smiles
N(C(=O)C1=CC(Cl)=C(O)C(Cl)=C1)C2=C3C(N=CN(CC4=C(OC(F)(F)F)C=CC=C4)C3=O)=C(Cl)C=C2
Molecular Formula
C23H13Cl3F3N3O4
Molecular Weight
558.72
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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