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HSD17B13-IN-42

Product Specifications

CAS Number

2770246-10-9

Target

Dehydrogenase

Related Pathways

Metabolism

Bioactivity

HSD17B13-IN-42 (compound 10) is a potent inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), with an IC50 of < 0.1 μM using estradiol as substrates. HSD17B13-IN-42 plays an important role in nonalcoholic fatty liver diseases (NAFLDs) including NASH (nonalcoholic steatohepatitis) [1].

Smiles

N(C(=O)C1=CC(Cl)=C(O)C(Cl)=C1)C2=C3C(N=CN(CC4=CC(OC(F)(F)F)=CC=C4)C3=O)=CC=C2

Molecular Formula

C23H14Cl2F3N3O4

Molecular Weight

524.28

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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