HSD17B13-IN-42
Product Specifications
CAS Number
2770246-10-9
Target
Dehydrogenase
Related Pathways
Metabolism
Bioactivity
HSD17B13-IN-42 (compound 10) is a potent inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), with an IC50 of < 0.1 μM using estradiol as substrates. HSD17B13-IN-42 plays an important role in nonalcoholic fatty liver diseases (NAFLDs) including NASH (nonalcoholic steatohepatitis) [1].
Smiles
N(C(=O)C1=CC(Cl)=C(O)C(Cl)=C1)C2=C3C(N=CN(CC4=CC(OC(F)(F)F)=CC=C4)C3=O)=CC=C2
Molecular Formula
C23H14Cl2F3N3O4
Molecular Weight
524.28
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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