HSD17B13-IN-40
Product Specifications
CAS Number
2770246-06-3
Target
Dehydrogenase
Related Pathways
Metabolism
Bioactivity
HSD17B13-IN-40 (compound 6) serves as a potent inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), exhibiting an IC50 value of less than 0.1 μM using estradiol as substrates. This compound is significant in the treatment of nonalcoholic fatty liver diseases (NAFLDs), including nonalcoholic steatohepatitis (NASH) [1].
Smiles
N(C(=O)C1=CC(Cl)=C(O)C(Cl)=C1)C2=C3C(N=CN(CC4=CC=C(C(F)(F)F)C=C4)C3=O)=CC=C2
Molecular Formula
C23H14Cl2F3N3O3
Molecular Weight
508.28
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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