HSD17B13-IN-36
Product Specifications
CAS Number
2730027-86-6
Target
Dehydrogenase
Related Pathways
Metabolism
Bioactivity
HSD17B13-IN-36 (compound 116) serves as a potent inhibitor of hydroxysteroid 17?-dehydrogenase 13 (HSD17B13), exhibiting an IC50 of <0.1 μM with estradiol as substrates. This compound is significant in the management of nonalcoholic fatty liver diseases (NAFLDs), including NASH (nonalcoholic steatohepatitis) [1].
Smiles
O(C1=NC(=NC=C1)C2=CC=C(C=C2)N3CCS(=O)(=O)CC3)C4=C(F)C(O)=C(F)C=C4
Molecular Formula
C20H17F2N3O4S
Molecular Weight
433.43
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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