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HSD17B13-IN-33

Product Specifications

CAS Number

2730027-85-5

Target

Dehydrogenase

Related Pathways

Metabolism

Bioactivity

HSD17B13-IN-33 (Compound 115), a potent inhibitor of hydroxysteroid 17?-dehydrogenase 13 (HSD17B13), exhibits an IC 50 of less than 0.1 ?M for estradiol. This compound is applicable in the research of liver diseases, metabolic disorders, and cardiovascular conditions including NAFLD, NASH, and drug-induced liver injury (DILI) [1].

Smiles

FC1=CC=C(OC2=NC(=NC=C2)C=3C=CC(=CC3)N4CCOCC4)C(F)=C1O

Molecular Formula

C20H17F2N3O3

Molecular Weight

385.36

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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