HSD17B13-IN-31
Product Specifications
CAS Number
2758802-33-2
Target
Dehydrogenase
Related Pathways
Metabolism
Bioactivity
HSD17B13-IN-31 (compound 32) serves as a highly effective inhibitor of hydroxysteroid 17?-dehydrogenase 13 (HSD17B13), demonstrating an IC50 of less than 0.1 μM and less than 1 μM when using estradiol and Leukotriene B3 as substrates, respectively. This compound is critical in managing nonalcoholic fatty liver diseases (NAFLDs), including nonalcoholic steatohepatitis (NASH) [1].
Smiles
N(C(=O)C1=CC(Cl)=C(O)C(Cl)=C1)C2=C(C(NCCC3=C(OC)C=CC=C3)=O)SC=C2
Molecular Formula
C21H18Cl2N2O4S
Molecular Weight
465.35
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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