HSD17B13-IN-31
Product Specifications
CAS Number
2758802-33-2
Target
Dehydrogenase
Related Pathways
Metabolism
Bioactivity
HSD17B13-IN-31 (compound 32) serves as a highly effective inhibitor of hydroxysteroid 17?-dehydrogenase 13 (HSD17B13), demonstrating an IC50 of less than 0.1 μM and less than 1 μM when using estradiol and Leukotriene B3 as substrates, respectively. This compound is critical in managing nonalcoholic fatty liver diseases (NAFLDs), including nonalcoholic steatohepatitis (NASH) [1].
Smiles
N(C(=O)C1=CC(Cl)=C(O)C(Cl)=C1)C2=C(C(NCCC3=C(OC)C=CC=C3)=O)SC=C2
Molecular Formula
C21H18Cl2N2O4S
Molecular Weight
465.35
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC472837-100 1x 100 µL
Desmoglein-3 (Squamous Cell Marker) (DSG3/2837), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC743648-500 1x 500 µL
SOX2 (Embryonic Stem Cell Marker) (rSOX2/1791), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC042243-100 1x 100 µL
Glutathione S-Transferase Mu3 (GSTM3) (CPTC-GSTMu3-1), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details