HSD17B13-IN-30
Product Specifications
CAS Number
2770246-58-5
Target
Dehydrogenase
Related Pathways
Metabolism
Bioactivity
HSD17B13-IN-30 (compound 64) serves as a potent inhibitor of hydroxysteroid 17?-dehydrogenase 13 (HSD17B13), exhibiting an IC 50 value of less than 0.1 μM? with estradiol? as substrates. This compound is significantly implicated in the management of nonalcoholic fatty liver diseases (NAFLDs), including nonalcoholic steatohepatitis (NASH) [1].
Smiles
N(C(=O)C1=CC(Cl)=C(O)C(Cl)=C1)C2=C3C(N=C(C)N(CC4=C(OC(F)(F)F)C=CC=C4)C3=O)=CC=C2
Molecular Formula
C24H16Cl2F3N3O4
Molecular Weight
538.3
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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