HSD17B13-IN-29
Product Specifications
CAS Number
2770246-48-3
Target
Dehydrogenase
Related Pathways
Metabolism
Bioactivity
Compound 53, also known as HSD17B13-IN-29, is an inhibitor targeting hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), demonstrating an IC 50 ≤ 0.1 μM for estradiol. This compound is applicable in the study of liver, metabolic, and cardiovascular diseases, including NAFLD and NASH, and for investigating drug-induced liver injury (DILI) [1].
Smiles
N(C(=O)C1=CC(Cl)=C(O)C(Cl)=C1)C2=C3C(N=CN(CC4=C(C#N)C=CC=C4)C3=O)=CC=C2
Molecular Formula
C23H14Cl2N4O3
Molecular Weight
465.29
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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