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HSD17B13-IN-18

Product Specifications

CAS Number

2758802-14-9

Target

Dehydrogenase

Related Pathways

Metabolism

Bioactivity

HSD17B13-IN-18 (compound 13) serves as a potent inhibitor of hydroxysteroid 17?-dehydrogenase 13 (HSD17B13), exhibiting IC50 values of < 0.1 μM for estradiol and < 1 μM for Leukotriene B3 as substrates. This compound is crucial in managing nonalcoholic fatty liver diseases (NAFLDs), including nonalcoholic steatohepatitis (NASH) [1].

Smiles

C(NCCC1=C(OC)C=CC=C1)(=O)C2=C(NC(=O)C3=CC(Cl)=C(O)C=C3)SC=C2

Molecular Formula

C21H19ClN2O4S

Molecular Weight

430.9

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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