HSD17B13-IN-18
Product Specifications
CAS Number
2758802-14-9
Target
Dehydrogenase
Related Pathways
Metabolism
Bioactivity
HSD17B13-IN-18 (compound 13) serves as a potent inhibitor of hydroxysteroid 17?-dehydrogenase 13 (HSD17B13), exhibiting IC50 values of ? 0.1 ?M for estradiol and ? 1 ?M for Leukotriene B3 as substrates. This compound is crucial in managing nonalcoholic fatty liver diseases (NAFLDs), including nonalcoholic steatohepatitis (NASH) [1].
Smiles
C(NCCC1=C(OC)C=CC=C1)(=O)C2=C(NC(=O)C3=CC(Cl)=C(O)C=C3)SC=C2
Molecular Formula
C21H19ClN2O4S
Molecular Weight
430.9
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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