HSD17B13-IN-17
Product Specifications
CAS Number
2758802-10-5
Target
Dehydrogenase
Related Pathways
Metabolism
Bioactivity
HSD17B13-IN-17 (compound 9) serves as a potent inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) . It demonstrates inhibitory efficacy with IC50 values of <0.1 μM for estradiol and <1 μM for Leukotriene B3 as substrates. This compound is significant in the management of nonalcoholic fatty liver diseases (NAFLDs), including nonalcoholic steatohepatitis (NASH) [1].
Smiles
C(NCCC1=C(F)C=CC=C1)(=O)C2=C(NC(=O)C3=CC(Cl)=C(O)C=C3)C=CS2
Molecular Formula
C20H16ClFN2O3S
Molecular Weight
418.87
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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