HSD17B13-IN-16
Product Specifications
CAS Number
2758802-09-2
Target
Dehydrogenase
Related Pathways
Metabolism
Bioactivity
HSD17B13-IN-16 (compound 8) serves as a potent inhibitor of hydroxysteroid 17?-dehydrogenase 13 (HSD17B13), demonstrating an IC50 of <0.1 ?M and <1 ?M when using estradiol and Leukotriene B3 as substrates, respectively. The compound is notably significant in the treatment of nonalcoholic fatty liver diseases (NAFLDs), including nonalcoholic steatohepatitis (NASH) [1].
Smiles
C(NCC1=C(OC)C=CC=C1)(=O)C2=C(NC(=O)C3=CC(Cl)=C(O)C=C3)C=CS2
Molecular Formula
C20H17ClN2O4S
Molecular Weight
416.88
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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