HSD17B13-IN-15
Product Specifications
CAS Number
2758802-07-0
Target
Dehydrogenase
Related Pathways
Metabolism
Bioactivity
HSD17B13-IN-15 (Compound 6) acts as an inhibitor targeting hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), exhibiting IC 50 values of ≤ 1 μM for leukotriene B3 and ≤ 0.1 μM for estradiol. This compound finds applications in studying various conditions, including liver diseases, metabolic disorders, and cardiovascular diseases such as NAFLD, NASH, or drug-induced liver injury (DILI) [1].
Smiles
C(NC1CC=2C(OC1)=CC=CC2)(=O)C3=C(NC(=O)C4=CC(Cl)=C(O)C=C4)C=CS3
Molecular Formula
C21H17ClN2O4S
Molecular Weight
428.89
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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