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HSD17B13-IN-11

Product Specifications

CAS Number

2758802-03-6

Target

Dehydrogenase

Related Pathways

Metabolism

Bioactivity

HSD17B13-IN-11 (Compound 2), with IC50 values of ≤ 1 μM for leukotriene B3 and ≤ 0.1 μM for estradiol, effectively inhibits hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) . This compound is utilized in studying various medical conditions including liver diseases, metabolic and cardiovascular disorders, particularly non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH), and drug-induced liver injury (DILI) [1].

Smiles

C(NCC(C)C)(=O)C1=C(NC(=O)C2=CC(Cl)=C(O)C=C2)C=CS1

Molecular Formula

C16H17ClN2O3S

Molecular Weight

352.84

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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