What is the catalog number for HPO-DAEE?

The catalog number for HPO-DAEE is T86592.

What sizes are available for HPO-DAEE?

HPO-DAEE is available in the following size(s): 25 mg, 50 mg, 100 mg.

How many pack sizes does HPO-DAEE come in?

HPO-DAEE is available in 3 different pack sizes.

Is HPO-DAEE in stock?

HPO-DAEE is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures HPO-DAEE?

HPO-DAEE is manufactured by Molfinity.

What is the estimated delivery time for HPO-DAEE?

Estimated delivery time for HPO-DAEE is approximately 10 business day(s), depending on your location.

HPO-DAEE

Product Specifications

CAS Number

1895934-61-8

Target

ROS, Reactive Oxygen Species, HDAC

Related Pathways

DNA Damage/DNA Repair, Metabolism, Immunology/Inflammation, Chromatin/Epigenetic, NF-κB

Bioactivity

HPO-DAEE (4-Hydroperoxy-2-decenoic acid ethyl ester) performs multiple roles in cellular processes, primarily enhancing nuclear accumulation of Nrf2 and activating the antioxidant response element (ARE) . It upregulates antioxidant genes such as HO-1 through Nrf2-ARE signaling and initiates the generation of reactive oxygen species. Additionally, HPO-DAEE inhibits histone deacetylase, promoting the expression of extracellular superoxide dismutase via histone acetylation. It offers protection against 6-hydroxydopamine-induced cell death by activating the Nrf2-ARE and eIF2α-ATF4 pathways [1].