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HDAC6-IN-33

Product Specifications

CAS Number

2444302-23-0

Target

HDAC

Related Pathways

Chromatin/Epigenetic, DNA Damage/DNA Repair

Bioactivity

HDAC6-IN-33 (compound 6), an irreversible and selective HDAC6 inhibitor, demonstrates a potency with an IC 50 of 193 nM and lacks activity against HDAC1-4. This compound adheres to HDAC6 through a two-step slow-binding mechanism, establishing it as a tight-binding inhibitor [1].

Smiles

C(F)(F)C=1OC(=NN1)C=2C=NC(NCC3=CC=CC=C3)=NC2

Molecular Formula

C14H11F2N5O

Molecular Weight

303.27

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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