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HC-5404

Product Specifications

CAS Number

2247396-91-2

Target

PERK

Related Pathways

Apoptosis

Purity

0.9933

Bioactivity

HC-5404 is a novel, potent and highly selective PERK (Protein kinase RNA-like Endoplasmic Reticulum Kinase) inhibitor, blocking the activation of the PERK pathway, which in turn inhibits the endoplasmic reticulum stress response signaling pathway, thereby exerting anti-tumor effects, and can be used to treat advanced solid tumors and renal cell Cancer.

Smiles

CC1=C(C=2C=C(C(NC(C)C)=O)C(N)=NC2)C=CC(NC([C@H](O)C3=CC(F)=CC(F)=C3)=O)=C1

Molecular Formula

C24H24F2N4O3

Molecular Weight

454.47

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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