GW814408X
Product Specifications
CAS Number
886599-05-9
Target
Aurora Kinase, Others
Related Pathways
Chromatin/Epigenetic, Others, Cell Cycle/Checkpoint
Bioactivity
GW814408X, a kinase chemical genome group (KCGS) compound, inhibits the AURKC kinase, which is involved in cell cycle progression, checkpoint regulation, and cell division. It exhibits cell line-dependent toxicity, such as cytotoxic effects on HeLa cells, and acts as a protein kinase inhibitor across ATP-dependent and -independent luciferases, potentially impacting Fluc reporter assays [1].
Smiles
N(N=CC=1C=CN=CC1)C2=C3C(C(=CN3)C4=CC(OC)=CC=C4)=NC=N2
Molecular Formula
C19H16N6O
Molecular Weight
344.37
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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