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GW694590A

Product Specifications

CAS Number

948313-24-4

Target

PDGFR, c-Kit, c-Myc, Discoidin Domain Receptor (DDR)

Related Pathways

Tyrosine Kinase/Adaptors, Angiogenesis, Cell Cycle/Checkpoint

Bioactivity

GW694590A (UNC10112731) functions as a MYC protein stabilizer that enhances the levels of endogenous MYC protein. It also acts on receptor tyrosine kinases, inhibiting DDR2, KIT, and PDGFRα by 81%, 68%, and 67% at a concentration of 1 μM, respectively. As a protein kinase inhibitor, GW694590A affects both ATP-dependent and ATP-independent luciferases, potentially influencing the Fluc reporter gene [1].

Smiles

N(C(OC)=O)C=1NC=2C(N1)=CC=C(OC3=CC=C(NC(NC4=CC=CC=C4)=O)C=C3)C2

Molecular Formula

C22H19N5O4

Molecular Weight

417.42

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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