GW549390X
Product Specifications
CAS Number
135307-33-4
Target
Others, VEGFR
Related Pathways
Others, Angiogenesis, Tyrosine Kinase/Adaptors
Bioactivity
GW549390X is a dual inhibitor targeting both Fluc and VEGFR2, with IC50 values of 0.26 μM and 1.2 μM, respectively. This compound binds to the ATP pocket of FLuc via the aniline side chain, functioning as an ATP-competitive inhibitor of Fluc. It serves as a protein kinase inhibitor across ATP-dependent and -independent luciferases, potentially affecting Fluc reporter assays [1].
Smiles
N(C=1OC(=CN1)C2=CC=CC=C2)C3=CC=CC=C3
Molecular Formula
C15H12N2O
Molecular Weight
236.27
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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