GTI 2040
Product Specifications
CAS Number
236391-66-5
Target
DNA/RNA Synthesis
Related Pathways
Cell Cycle/Checkpoint, DNA Damage/DNA Repair
Bioactivity
GTI-2040, a 20-mer phosphorothioate oligonucleotide, targets the mRNA sequence of human ribonucleotide reductase R2 for hybridization. This compound inhibits cancer cell proliferation by reducing R2 expression in vitro and markedly suppresses tumor growth in xenograft models of human cancer in mice.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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