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GTI 2040

Product Specifications

CAS Number

236391-66-5

Target

DNA/RNA Synthesis

Related Pathways

Cell Cycle/Checkpoint, DNA Damage/DNA Repair

Bioactivity

GTI-2040, a 20-mer phosphorothioate oligonucleotide, targets the mRNA sequence of human ribonucleotide reductase R2 for hybridization. This compound inhibits cancer cell proliferation by reducing R2 expression in vitro and markedly suppresses tumor growth in xenograft models of human cancer in mice.

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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