GSK248233A
Product Specifications
CAS Number
850665-21-3
Target
VEGFR, Others
Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis, Others
Bioactivity
GSK248233A is a dual inhibitor targeting Fluc and VEGFR2, exhibiting IC50 values of 1.03 μM and 2 nM, respectively. Additionally, it demonstrates activity against the AGC family and functions as a protein kinase inhibitor for both ATP-dependent and -independent luciferases, potentially impacting Fluc reporter assays [1].
Smiles
C(C)N1C=2C(N=C1C3=NON=C3N)=CN=C(OC4=CC(NC(=O)C5=CC=C(N(C)C)C=C5)=CC=C4)C2
Molecular Formula
C25H24N8O3
Molecular Weight
484.51
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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