GNE-555
Product Specifications
CAS Number
1428902-71-9
Target
MTOR
Related Pathways
PI3K/Akt/mTOR signaling
Bioactivity
GNE-555, a selective and metabolically stable mTOR inhibitor (K i=1.5 nM), demonstrates good oral bioavailability and antiproliferative activity on PC3 and MCF-7 cells, making it suitable for cancer research [1] [2].
Smiles
C[C@@H]1N(C2=C3C([C@@]4(N([C@](C3)(CC4)[H])C5COC5)[H])=NC(=N2)C6=CC=C(NC(NCC)=O)C=C6)CCOC1
Molecular Formula
C26H34N6O3
Molecular Weight
478.59
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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