Galectin-3-IN-4
Product Specifications
CAS Number
2496515-38-7
Target
Galectin
Related Pathways
Immunology/Inflammation
Bioactivity
Galectin-3-IN-4 (compound 5), a carboxamide analog, effectively and selectively inhibits both human and mouse galectin-3. This compound demonstrates notable potency with IC50 values of 21 nM for hGal-3 and 167 nM for mGal-3. It is also orally bioavailable. For other galectins, Galectin-3-IN-4 shows IC50 values of 1580 nM for hGal-1 and 2750 nM for hGal-9, respectively [1].
Smiles
O(C)[C@@H]1[C@H]([C@@H](O)[C@@H](CO)O[C@H]1C(N(C)C=2C=C3C(=CC2)N=CS3)=O)N4C=C(N=N4)C5=C(F)C(F)=C(Cl)C=C5
Molecular Formula
C24H22ClF2N5O5S
Molecular Weight
565.98
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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