FL77-24
Product Specifications
CAS Number
2413582-39-3
Target
Apoptosis
Related Pathways
Apoptosis
Bioactivity
FL77-24, an analog of FL118 and an apoptosis inducer, exhibits antitumor activity with IC50 values of 99.4 nM in HCT116 cells, 118 nM in HepG2 cells, less than 6.4 nM in both MCF-7 and HeLa cells, and 28.5 nM in A549 cells. It primarily induces cell cycle arrest in the S and G2/M phases [1].
Smiles
O(C)C=1C=C(C2=C3C(C=4N(C3)C(=O)C5=C(C4)[C@](CC)(O)C(=O)OC5)=NC=6C2=CC7=C(C6)OCO7)C=C(OC)C1
Molecular Formula
C29H24N2O8
Molecular Weight
528.51
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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