FKBP51-Hsp90-IN-2
Product Specifications
CAS Number
601511-07-3
Target
FKBP|||HSP
Related Pathways
Metabolism|||Apoptosis|||Autophagy|||Cytoskeletal Signaling|||Immunology/Inflammation
Bioactivity
FKBP51-Hsp90-IN-2 (Compound E08) functions as a selective inhibitor for the FKBP51 - Hsp90 protein-protein interaction, exhibiting IC 50 values of 0.4 µM for FKBP51 and 5 µM for FKBP52. Beyond its inhibitory actions, FKBP51-Hsp90-IN-2 enhances cellular energy metabolism and promotes neurite growth. This compound is utilized in the study of neurodegenerative diseases and cancer [1].
Smiles
O=C(NC1=CC=C(NC(=O)CC)C(=C1)C)CSC2=NC3=CC4=C(C=C3C=C2C)CCC4
Molecular Formula
C25H27N3O2S
Molecular Weight
433.57
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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