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FGFR4-IN-17

Product Specifications

CAS Number

3011805-61-8

Target

FGFR

Related Pathways

Tyrosine Kinase/Adaptors, Angiogenesis

Bioactivity

FGFR4-IN-17 (Compound (S) -23), a piperazinyl diflurindan derivative featuring a pyridinyl group, functions as an inhibitor of FGFR. It exhibits IC 50 values of 24.2 nM for FGFR1, 16.1 nM for FGFR2, 78.0 nM for FGFR3, and 68.0 nM for FGFR4. Notably, FGFR4-IN-17 demonstrates significant antitumor activity [1].

Smiles

FC1(F)C=2C([C@H](C1)N3CCN(C)CC3)=CC=C(NC(=O)C4=CC(C#CC=5C=C(OC)C=NC5)=C(F)C=C4)C2

Molecular Formula

C29H27F3N4O2

Molecular Weight

520.55

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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