FAK-IN-20
Product Specifications
CAS Number
3004967-41-0
Target
FAK, Apoptosis
Related Pathways
Cytoskeletal Signaling, Tyrosine Kinase/Adaptors, Apoptosis, Angiogenesis
Bioactivity
FAK-IN-20 (Compound 7b), a potent FAK inhibitor, demonstrates an IC 50 of 0.27 nM and exhibits anticancer properties. This compound arrests the cell cycle in the G2/M phase and induces cell apoptosis (apoptosis) through the generation of ROS [1].
Smiles
N(C1=C(OC)C=C(NS(CCN2C[C@@H](C)O[C@@H](C)C2)(=O)=O)C=C1)C=3N=C(NC4=C(C(NC)=O)C=CC=C4)C(Cl)=CN3
Molecular Formula
C27H34ClN7O5S
Molecular Weight
604.12
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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