FAK/aurora kinase-IN-1
Product Specifications
CAS Number
2178117-69-4
Target
Aurora Kinase, FAK
Related Pathways
Cell Cycle/Checkpoint, Tyrosine Kinase/Adaptors, Angiogenesis, Cytoskeletal Signaling, Chromatin/Epigenetic
Bioactivity
FAK/aurora kinase-IN-1, a dual inhibitor of FAK and aurora kinase, has IC50 values of 6.61 nM and 0.91 nM respectively, and demonstrates anticancer effects (WO2018019252A1; compound 11) [1].
Smiles
C(C(N(C)C)=O)(=O)C1=C(NC2=NC(NC=3C=CC(=NC3)N4CCOCC4)=NC=C2Cl)C=CC=C1
Molecular Formula
C23H24ClN7O3
Molecular Weight
481.93
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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