FAK/aurora kinase-IN-1

Product Specifications

CAS Number

2178117-69-4

Target

Aurora Kinase|||FAK

Related Pathways

Cell Cycle/Checkpoint|||Tyrosine Kinase/Adaptors|||Angiogenesis|||Cytoskeletal Signaling|||Chromatin/Epigenetic

Bioactivity

FAK/aurora kinase-IN-1, a dual inhibitor of FAK and aurora kinase, has IC50 values of 6.61 nM and 0.91 nM respectively, and demonstrates anticancer effects (WO2018019252A1; compound 11) [1].

Smiles

C(C(N(C)C)=O)(=O)C1=C(NC2=NC(NC=3C=CC(=NC3)N4CCOCC4)=NC=C2Cl)C=CC=C1

Molecular Formula

C23H24ClN7O3

Molecular Weight

481.93

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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