ETC-168
Product Specifications
CAS Number
1464150-99-9
Target
MNK
Related Pathways
MAPK
Bioactivity
ETC-168 is a selective, orally active MNK inhibitor with IC50 values of 23 nM for MNK1 and 43 nM for MNK2. It demonstrates antiproliferative efficacy both in vivo and in vitro [1].
Smiles
C(#N)C1=CC=C(C=2N3C(=NC2)C=CC(=N3)C4=CC=C(C(=O)N5CCOCC5)C=C4)C=C1
Molecular Formula
C24H19N5O2
Molecular Weight
409.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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