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ETC-168

Product Specifications

CAS Number

1464150-99-9

Target

MNK

Related Pathways

MAPK

Bioactivity

ETC-168 is a selective, orally active MNK inhibitor with IC50 values of 23 nM for MNK1 and 43 nM for MNK2. It demonstrates antiproliferative efficacy both in vivo and in vitro [1].

Smiles

C(#N)C1=CC=C(C=2N3C(=NC2)C=CC(=N3)C4=CC=C(C(=O)N5CCOCC5)C=C4)C=C1

Molecular Formula

C24H19N5O2

Molecular Weight

409.44

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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