Ent- (+) -Verticilide
Product Specifications
CAS Number
2056011-05-1
Target
Calcium Channel
Related Pathways
Metabolism|||Membrane transporter/Ion channel
Bioactivity
Ent- (+) -verticilide is an effective and specific inhibitor of cardiac ryanodine receptor (RyR2) calcium release channels, demonstrating antiarrhythmic properties. It suppresses RyR2-mediated diastolic Ca2+ leak and shows greater potency and a unique action mechanism compared to Dantrolene and Tetracaine. ent- (+) -verticilide serves as a valuable tool for exploring the therapeutic potential of addressing RyR2 hyperactivity in cardiac and neurological conditions [1].
Smiles
C(CCCC)[C@H]1C(=O)N(C)[C@H](C)C(=O)O[C@@H](CCCCC)C(=O)N(C)[C@H](C)C(=O)O[C@@H](CCCCC)C(=O)N(C)[C@H](C)C(=O)O[C@@H](CCCCC)C(=O)N(C)[C@H](C)C(=O)O1
Molecular Formula
C44H76N4O12
Molecular Weight
853.09
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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