EGFR-IN-104
Product Specifications
CAS Number
2758904-45-7
Target
EGFR
Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis, JAK/STAT signaling
Bioactivity
EGFR-IN-104 (Compound A23) acts as a potent EGFR inhibitor, demonstrating IC50 values of 0.33 μM for EGFR L858R/T790M and 0.133 μM for EGFR Del19/T790M/C797S. It exhibits anticancer properties, effective both in vitro and in vivo [1].
Smiles
OC1=C(C2=NC(NCC=3C=NC(=NC3)N4CCN(C)CC4)=C5C(=N2)CCSC5)C=CC=C1
Molecular Formula
C23H27N7OS
Molecular Weight
449.57
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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