EGFR/HER2-IN-12
Product Specifications
CAS Number
2237230-21-4
Target
EGFR
Related Pathways
Angiogenesis, JAK/STAT signaling, Tyrosine Kinase/Adaptors
Bioactivity
EGFR/HER2-IN-12 (compound 14b) serves as a dual inhibitor targeting EGFR and HER2, demonstrating 81% and 51% inhibition respectively at a concentration of 10 μM. This compound exhibits minimal toxicity towards A431 and MDA-MB-361 cancer cells [1].
Smiles
N(C1=C2C(SC(=C2)C3=CC=C(N(=O)=O)C=C3)=NC=N1)C4=CC(Cl)=C(OC5=CC(C)=CC=C5)C=C4
Molecular Formula
C25H17ClN4O3S
Molecular Weight
488.95
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
NBP2-32999-0.1mg 0.1 mg
Mouse Monoclonal TTF1 / NKX2.1 Antibody (SPM150)
Sign In for Pricing
View Details MBS9339127-01 48 Well
Mouse Vacuolar protein sorting-associated protein 13B, VPS13B ELISA Kit
Sign In for Pricing
View Details MBS9339127-02 96 Well
Mouse Vacuolar protein sorting-associated protein 13B, VPS13B ELISA Kit
Sign In for Pricing
View Details MBS9339127-03 5x 96 Well
Mouse Vacuolar protein sorting-associated protein 13B, VPS13B ELISA Kit
Sign In for Pricing
View Details MBS9339127-04 10x 96 Well
Mouse Vacuolar protein sorting-associated protein 13B, VPS13B ELISA Kit
Sign In for Pricing
View Details MBS1223148 Inquire
Recombinant Shewanella amazonensis Catalase-peroxidase 1 (katG1), partial
Sign In for Pricing
View Details