EGFR T790M/L858R-IN-6
Product Specifications
CAS Number
3032760-71-4
Target
EGFR
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors, JAK/STAT signaling
Bioactivity
EGFR T790M/L858R-IN-6 (compound 53), classified as a pyrimidine compound, serves as an effective inhibitor of EGFR T790M/L858R, demonstrating 90.88% inhibition of enzyme activity at a concentration of 0.05 μM [1].
Smiles
CN1C=C(C=2C1=CC=CC2)C3=NC(NC4=C(OC)C=C(NCCO)C(NC5=CC=CC=N5)=C4)=NC=C3
Molecular Formula
C27H27N7O2
Molecular Weight
481.55
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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