EGFR T790M/L858R-IN-5

Product Specifications

CAS Number

3032760-70-3

Target

EGFR

Related Pathways

Angiogenesis|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors

Bioactivity

EGFR T790M/L858R-IN-5 (example 52) functions as a potent EGFR T790M/L858R inhibitor, demonstrating a 92.9% inhibition rate at a concentration of 0.05 ?M [1].

Smiles

CN1C=C(C=2C1=CC=CC2)C3=NC(NC4=C(OC)C=C(NCCN(C)C)C(NC=5C=CN=CN5)=C4)=NC=C3

Molecular Formula

C28H31N9O

Molecular Weight

509.61

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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