Ebselen derivative 1
Product Specifications
CAS Number
3030492-59-9
Target
Apoptosis, Ferroptosis
Related Pathways
Apoptosis
Bioactivity
Ebselen derivative 1 (Compound 19), an orally active glutathione peroxidase (GPx) mimic, exhibits notable protective effects against cisplatin-induced hair cell (HC) damage in both in vitro and in vivo settings. It significantly reduces oxidative stress, apoptosis, and ferroptosis in hair cells, making it useful in the study of cisplatin-induced hearing loss [1].
Smiles
O(C)C1=C2C(C(=O)N([Se]2)C=3C=CC=NC3)=CC=C1
Molecular Formula
C13H10N2O2Se
Molecular Weight
305.19
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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